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Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma

BACKGROUND: Most patients with hormone receptor (HR)-positive, human epidermal growth factor receptor type 2 (HER2)-negative breast cancer can be cured by surgery and endocrine therapy, but a significant proportion suffer recurrences. Actinin-4 is associated with cancer invasion and metastasis, and...

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Detalles Bibliográficos
Autores principales: Sugano, Teppei, Yoshida, Masayuki, Masuda, Mari, Ono, Makiko, Tamura, Kenji, Kinoshita, Takayuki, Tsuda, Hitoshi, Honda, Kazufumi, Gemma, Akihiko, Yamada, Tesshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283275/
https://www.ncbi.nlm.nih.gov/pubmed/32265507
http://dx.doi.org/10.1038/s41416-020-0821-y