An anticonvulsive drug, valproic acid (valproate), has effects on the biosynthesis of fatty acids and polyketides in microorganisms

Valproic acid or valproate (VPA) is an anticonvulsive drug used for treatments of epilepsy, bipolar disorder, and migraine headaches. VPA is also an epigenetic modulator, inhibiting histone deacetylase, and it has been subjected to clinical study for cancer treatment. During the investigation of VPA...

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Detalles Bibliográficos
Autores principales: Poolchanuan, Prapassorn, Unagul, Panida, Thongnest, Sanit, Wiyakrutta, Suthep, Ngamrojanavanich, Nattaya, Mahidol, Chulabhorn, Ruchirawat, Somsak, Kittakoop, Prasat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283484/
https://www.ncbi.nlm.nih.gov/pubmed/32518288
http://dx.doi.org/10.1038/s41598-020-66251-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283484/
https://www.ncbi.nlm.nih.gov/pubmed/32518288
http://dx.doi.org/10.1038/s41598-020-66251-y

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