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An anticonvulsive drug, valproic acid (valproate), has effects on the biosynthesis of fatty acids and polyketides in microorganisms
Valproic acid or valproate (VPA) is an anticonvulsive drug used for treatments of epilepsy, bipolar disorder, and migraine headaches. VPA is also an epigenetic modulator, inhibiting histone deacetylase, and it has been subjected to clinical study for cancer treatment. During the investigation of VPA...
Autores principales: | Poolchanuan, Prapassorn, Unagul, Panida, Thongnest, Sanit, Wiyakrutta, Suthep, Ngamrojanavanich, Nattaya, Mahidol, Chulabhorn, Ruchirawat, Somsak, Kittakoop, Prasat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283484/ https://www.ncbi.nlm.nih.gov/pubmed/32518288 http://dx.doi.org/10.1038/s41598-020-66251-y |
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