Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review

There is a growing evidence for the rapid and robust antidepressive effect of ketamine in unipolar and bipolar treatment resistant depression although evidence for the risk of affective switch is still limited. This case presents bipolar I disorder patient with treatment resistant depressive episode...

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Autores principales: Wilkowska, Alina, Szałach, Łukasz, Słupski, Jakub, Wielewicka, Aleksandra, Czarnota, Małgorzata, Gałuszko-Węgielnik, Maria, Wiglusz, Mariusz S., Cubała, Wiesław J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283492/
https://www.ncbi.nlm.nih.gov/pubmed/32581886
http://dx.doi.org/10.3389/fpsyt.2020.00516
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author Wilkowska, Alina
Szałach, Łukasz
Słupski, Jakub
Wielewicka, Aleksandra
Czarnota, Małgorzata
Gałuszko-Węgielnik, Maria
Wiglusz, Mariusz S.
Cubała, Wiesław J.
author_facet Wilkowska, Alina
Szałach, Łukasz
Słupski, Jakub
Wielewicka, Aleksandra
Czarnota, Małgorzata
Gałuszko-Węgielnik, Maria
Wiglusz, Mariusz S.
Cubała, Wiesław J.
author_sort Wilkowska, Alina
collection PubMed
description There is a growing evidence for the rapid and robust antidepressive effect of ketamine in unipolar and bipolar treatment resistant depression although evidence for the risk of affective switch is still limited. This case presents bipolar I disorder patient with treatment resistant depressive episode experiencing a switch to manic episode with mixed features shortly after receiving eight subanaesthetic doses of oral ketamine as an add-on treatment preceded by 2-day period of manic symptoms.
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spelling pubmed-72834922020-06-23 Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review Wilkowska, Alina Szałach, Łukasz Słupski, Jakub Wielewicka, Aleksandra Czarnota, Małgorzata Gałuszko-Węgielnik, Maria Wiglusz, Mariusz S. Cubała, Wiesław J. Front Psychiatry Psychiatry There is a growing evidence for the rapid and robust antidepressive effect of ketamine in unipolar and bipolar treatment resistant depression although evidence for the risk of affective switch is still limited. This case presents bipolar I disorder patient with treatment resistant depressive episode experiencing a switch to manic episode with mixed features shortly after receiving eight subanaesthetic doses of oral ketamine as an add-on treatment preceded by 2-day period of manic symptoms. Frontiers Media S.A. 2020-06-03 /pmc/articles/PMC7283492/ /pubmed/32581886 http://dx.doi.org/10.3389/fpsyt.2020.00516 Text en Copyright © 2020 Wilkowska, Szałach, Słupski, Wielewicka, Czarnota, Gałuszko-Węgielnik, Wiglusz and Cubała http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Wilkowska, Alina
Szałach, Łukasz
Słupski, Jakub
Wielewicka, Aleksandra
Czarnota, Małgorzata
Gałuszko-Węgielnik, Maria
Wiglusz, Mariusz S.
Cubała, Wiesław J.
Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review
title Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review
title_full Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review
title_fullStr Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review
title_full_unstemmed Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review
title_short Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review
title_sort affective switch associated with oral, low dose ketamine treatment in a patient with treatment resistant bipolar i depression. case report and literature review
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283492/
https://www.ncbi.nlm.nih.gov/pubmed/32581886
http://dx.doi.org/10.3389/fpsyt.2020.00516
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