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Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation
As a kind of green additive, pectic oligosaccharide (POS) may regulate some physiological functions of animals, such as gut health, antioxidant capacity, immunity and lipid metabolism. This study aimed to identify whether POS administration can improve maternal reproduction, and to determine the pos...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283514/ https://www.ncbi.nlm.nih.gov/pubmed/32542202 http://dx.doi.org/10.1016/j.aninu.2020.01.003 |
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author | Liu, Minghui Mao, Xiangbing Chen, Daiwen Yu, Bing He, Jun Zheng, Ping Yu, Jie Luo, Junqiu Luo, Yuheng Wang, Jianping Wang, Quyuan Wang, Huifen |
author_facet | Liu, Minghui Mao, Xiangbing Chen, Daiwen Yu, Bing He, Jun Zheng, Ping Yu, Jie Luo, Junqiu Luo, Yuheng Wang, Jianping Wang, Quyuan Wang, Huifen |
author_sort | Liu, Minghui |
collection | PubMed |
description | As a kind of green additive, pectic oligosaccharide (POS) may regulate some physiological functions of animals, such as gut health, antioxidant capacity, immunity and lipid metabolism. This study aimed to identify whether POS administration can improve maternal reproduction, and to determine the possible metabolism. A total of 48 pregnant Wistar rats randomly allotted into 2 groups, and each group was fed a diet supplemented with 0 or 800 mg/kg of POS. Pectic oligosaccharide administration increased rat born number (P < 0.05), did not affect rat embryo number on d 7 of gestation, but increased rat fetus number on d 14 of gestation (P < 0.05). On d 14 of gestation, POS treatment improved Lactobacillus and Bifidobacterium populations and volatile fatty acid concentrations of cecal digesta (P < 0.05), hormone (progesterone and nitric oxide) and cytokine (interleukin 2) concentrations of serum (P < 0.05), and antioxidant capacity of serum (increased total antioxidant capacity and decreased malondialdehyde) and placenta (increased total superoxide dismutase, decreased malondialdehyde) (P < 0.05) in pregnant rats. These results suggest that POS administration improved rat reproduction via decreasing fetus loss in middle gestation. This was due to the increased volatile fatty acid concentrations in rat gut improving hormone and inflammatory-cytokine productions, and antioxidant capacity. |
format | Online Article Text |
id | pubmed-7283514 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-72835142020-06-14 Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation Liu, Minghui Mao, Xiangbing Chen, Daiwen Yu, Bing He, Jun Zheng, Ping Yu, Jie Luo, Junqiu Luo, Yuheng Wang, Jianping Wang, Quyuan Wang, Huifen Anim Nutr FEED EVALUATION As a kind of green additive, pectic oligosaccharide (POS) may regulate some physiological functions of animals, such as gut health, antioxidant capacity, immunity and lipid metabolism. This study aimed to identify whether POS administration can improve maternal reproduction, and to determine the possible metabolism. A total of 48 pregnant Wistar rats randomly allotted into 2 groups, and each group was fed a diet supplemented with 0 or 800 mg/kg of POS. Pectic oligosaccharide administration increased rat born number (P < 0.05), did not affect rat embryo number on d 7 of gestation, but increased rat fetus number on d 14 of gestation (P < 0.05). On d 14 of gestation, POS treatment improved Lactobacillus and Bifidobacterium populations and volatile fatty acid concentrations of cecal digesta (P < 0.05), hormone (progesterone and nitric oxide) and cytokine (interleukin 2) concentrations of serum (P < 0.05), and antioxidant capacity of serum (increased total antioxidant capacity and decreased malondialdehyde) and placenta (increased total superoxide dismutase, decreased malondialdehyde) (P < 0.05) in pregnant rats. These results suggest that POS administration improved rat reproduction via decreasing fetus loss in middle gestation. This was due to the increased volatile fatty acid concentrations in rat gut improving hormone and inflammatory-cytokine productions, and antioxidant capacity. KeAi Publishing 2020-06 2020-01-23 /pmc/articles/PMC7283514/ /pubmed/32542202 http://dx.doi.org/10.1016/j.aninu.2020.01.003 Text en © 2020 Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | FEED EVALUATION Liu, Minghui Mao, Xiangbing Chen, Daiwen Yu, Bing He, Jun Zheng, Ping Yu, Jie Luo, Junqiu Luo, Yuheng Wang, Jianping Wang, Quyuan Wang, Huifen Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
title | Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
title_full | Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
title_fullStr | Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
title_full_unstemmed | Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
title_short | Dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
title_sort | dietary pectic oligosaccharide supplementation improves rat reproductive performance via regulating intestinal volatile fatty acids during middle gestation |
topic | FEED EVALUATION |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283514/ https://www.ncbi.nlm.nih.gov/pubmed/32542202 http://dx.doi.org/10.1016/j.aninu.2020.01.003 |
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