Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells

At least 200 single-nucleotide polymorphisms (SNPs) are associated with multiple sclerosis (MS) risk. A key function that could mediate SNP-encoded MS risk is their regulatory effects on gene expression. We performed microarrays using RNA extracted from purified immune cell types from 73 untreated M...

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Detalles Bibliográficos
Autores principales: Gresle, Melissa M, Jordan, Margaret A, Stankovich, Jim, Spelman, Tim, Johnson, Laura J, Laverick, Louise, Hamlett, Alison, Smith, Letitia D, Jokubaitis, Vilija G, Baker, Josephine, Haartsen, Jodi, Taylor, Bruce, Charlesworth, Jac, Bahlo, Melanie, Speed, Terence P, Brown, Matthew A, Field, Judith, Baxter, Alan G, Butzkueven, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
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Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283543/
https://www.ncbi.nlm.nih.gov/pubmed/32518073
http://dx.doi.org/10.26508/lsa.202000650

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