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Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic

BACKGROUND: Data on the development of Covid‐19 among people with intellectual disabilities (IDs) are scarce and it is uncertain to what extent general population data applies to people with ID. To give an indication of possible implications, this study investigated excess mortality patterns during...

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Autores principales: Cuypers, M., Schalk, B. W. M., Koks‐Leensen, M. C. J., Nägele, M. E., Bakker‐van Gijssel, E. J., Naaldenberg, J., Leusink, G. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283786/
https://www.ncbi.nlm.nih.gov/pubmed/32458565
http://dx.doi.org/10.1111/jir.12739
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author Cuypers, M.
Schalk, B. W. M.
Koks‐Leensen, M. C. J.
Nägele, M. E.
Bakker‐van Gijssel, E. J.
Naaldenberg, J.
Leusink, G. L.
author_facet Cuypers, M.
Schalk, B. W. M.
Koks‐Leensen, M. C. J.
Nägele, M. E.
Bakker‐van Gijssel, E. J.
Naaldenberg, J.
Leusink, G. L.
author_sort Cuypers, M.
collection PubMed
description BACKGROUND: Data on the development of Covid‐19 among people with intellectual disabilities (IDs) are scarce and it is uncertain to what extent general population data applies to people with ID. To give an indication of possible implications, this study investigated excess mortality patterns during a previous influenza epidemic. METHODS: Using Dutch population and mortality registers, a historical cohort study was designed to compare mortality during the 2017–2018 influenza epidemic with mortality in the same period in the three previous years. People with ID were identified by entitlements to residential ID‐care services as retrieved from a national database. RESULTS: Data covered the entire adult Dutch population (12.6 million; GenPop), of which 91 064 individuals were identified with an ID. During the influenza epidemic, mortality among people with ID increased almost three times as much than in the GenPop (15.2% vs. 5.4%), and more among male individuals with ID (+19.5%) than among female individuals with ID (+10.6%), as compared with baseline. In both cohorts, comparable increases in mortality within older age groups and due to respiratory causes were seen. Particularly in the ID‐cohort, excess deaths also occurred in younger age groups, due to endocrine diseases and ID‐specific causes. CONCLUSIONS: During the 2017–2018 influenza epidemic, excess mortality among people with ID was three times higher than in the general Dutch population, appeared more often at young age and with a broader range of underlying causes. These findings suggest that a pandemic may disproportionally affect people with ID while population data may not immediately raise warnings. Early detection of diverging patterns and faster implementation of tailored strategies therefore require collection of good quality data.
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spelling pubmed-72837862020-06-10 Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic Cuypers, M. Schalk, B. W. M. Koks‐Leensen, M. C. J. Nägele, M. E. Bakker‐van Gijssel, E. J. Naaldenberg, J. Leusink, G. L. J Intellect Disabil Res COVID‐19 Special Section BACKGROUND: Data on the development of Covid‐19 among people with intellectual disabilities (IDs) are scarce and it is uncertain to what extent general population data applies to people with ID. To give an indication of possible implications, this study investigated excess mortality patterns during a previous influenza epidemic. METHODS: Using Dutch population and mortality registers, a historical cohort study was designed to compare mortality during the 2017–2018 influenza epidemic with mortality in the same period in the three previous years. People with ID were identified by entitlements to residential ID‐care services as retrieved from a national database. RESULTS: Data covered the entire adult Dutch population (12.6 million; GenPop), of which 91 064 individuals were identified with an ID. During the influenza epidemic, mortality among people with ID increased almost three times as much than in the GenPop (15.2% vs. 5.4%), and more among male individuals with ID (+19.5%) than among female individuals with ID (+10.6%), as compared with baseline. In both cohorts, comparable increases in mortality within older age groups and due to respiratory causes were seen. Particularly in the ID‐cohort, excess deaths also occurred in younger age groups, due to endocrine diseases and ID‐specific causes. CONCLUSIONS: During the 2017–2018 influenza epidemic, excess mortality among people with ID was three times higher than in the general Dutch population, appeared more often at young age and with a broader range of underlying causes. These findings suggest that a pandemic may disproportionally affect people with ID while population data may not immediately raise warnings. Early detection of diverging patterns and faster implementation of tailored strategies therefore require collection of good quality data. John Wiley and Sons Inc. 2020-05-26 2020-07 /pmc/articles/PMC7283786/ /pubmed/32458565 http://dx.doi.org/10.1111/jir.12739 Text en © 2020 The Authors. Journal of Intellectual Disability Research published by MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle COVID‐19 Special Section
Cuypers, M.
Schalk, B. W. M.
Koks‐Leensen, M. C. J.
Nägele, M. E.
Bakker‐van Gijssel, E. J.
Naaldenberg, J.
Leusink, G. L.
Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic
title Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic
title_full Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic
title_fullStr Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic
title_full_unstemmed Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic
title_short Mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the Netherlands: potential implications for the COVID‐19 pandemic
title_sort mortality of people with intellectual disabilities during the 2017/2018 influenza epidemic in the netherlands: potential implications for the covid‐19 pandemic
topic COVID‐19 Special Section
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283786/
https://www.ncbi.nlm.nih.gov/pubmed/32458565
http://dx.doi.org/10.1111/jir.12739
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