Analysis of TCR Repertoire and PD-1 Expression in Decidual and Peripheral CD8(+) T Cells Reveals Distinct Immune Mechanisms in Miscarriage and Preeclampsia

CD8(+) T cells, the most abundant T cell subset in the decidua, play a critical role in the maintenance of pregnancy. The majority of decidual CD8(+) T cells have an effector memory phenotype, while those in the peripheral blood display a naive phenotype. An increased amount of highly differentiated...

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Detalles Bibliográficos
Autores principales: Morita, Keiko, Tsuda, Sayaka, Kobayashi, Eiji, Hamana, Hiroshi, Tsuda, Kei, Shima, Tomoko, Nakashima, Akitoshi, Ushijima, Akemi, Kishi, Hiroyuki, Saito, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283903/
https://www.ncbi.nlm.nih.gov/pubmed/32582176
http://dx.doi.org/10.3389/fimmu.2020.01082

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