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Format and geometries matter: Structure-based design defines the functionality of bispecific antibodies
Multispecific antibodies can be generated in different formats. More than two decades of R&D in the field of bispecific antibody engineering revealed that the design and choice of format can have a profound impact on the antibody functionality. This holds in particular true for entities that eli...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283971/ https://www.ncbi.nlm.nih.gov/pubmed/32542108 http://dx.doi.org/10.1016/j.csbj.2020.05.006 |