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uORF Shuffling Fine-Tunes Gene Expression at a Deep Level of the Process
Upstream open reading frames (uORFs) are present in the 5’ leader sequences (or 5’ untranslated regions) upstream of the protein-coding main ORFs (mORFs) in eukaryotic polycistronic mRNA. It is well known that a uORF negatively affects translation of the mORF. Emerging ribosome profiling approaches...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284334/ https://www.ncbi.nlm.nih.gov/pubmed/32403214 http://dx.doi.org/10.3390/plants9050608 |