Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer

Cancer is a chronic disease that is responsible for the high death rate, globally. The administration of anticancer drugs is one crucial approach that is employed for the treatment of cancer, although its therapeutic status is not presently satisfactory. The anticancer drugs are limited pharmacologi...

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Autores principales: Alven, Sibusiso, Nqoro, Xhamla, Buyana, Buhle, Aderibigbe, Blessing A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284459/
https://www.ncbi.nlm.nih.gov/pubmed/32365495
http://dx.doi.org/10.3390/pharmaceutics12050406
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author Alven, Sibusiso
Nqoro, Xhamla
Buyana, Buhle
Aderibigbe, Blessing A.
author_facet Alven, Sibusiso
Nqoro, Xhamla
Buyana, Buhle
Aderibigbe, Blessing A.
author_sort Alven, Sibusiso
collection PubMed
description Cancer is a chronic disease that is responsible for the high death rate, globally. The administration of anticancer drugs is one crucial approach that is employed for the treatment of cancer, although its therapeutic status is not presently satisfactory. The anticancer drugs are limited pharmacologically, resulting from the serious side effects, which could be life-threatening. Polymer drug conjugates, nano-based drug delivery systems can be utilized to protect normal body tissues from the adverse side effects of anticancer drugs and also to overcome drug resistance. They transport therapeutic agents to the target cell/tissue. This review article is based on the therapeutic outcomes of polymer-drug conjugates against breast and lung cancer.
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spelling pubmed-72844592020-06-19 Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer Alven, Sibusiso Nqoro, Xhamla Buyana, Buhle Aderibigbe, Blessing A. Pharmaceutics Review Cancer is a chronic disease that is responsible for the high death rate, globally. The administration of anticancer drugs is one crucial approach that is employed for the treatment of cancer, although its therapeutic status is not presently satisfactory. The anticancer drugs are limited pharmacologically, resulting from the serious side effects, which could be life-threatening. Polymer drug conjugates, nano-based drug delivery systems can be utilized to protect normal body tissues from the adverse side effects of anticancer drugs and also to overcome drug resistance. They transport therapeutic agents to the target cell/tissue. This review article is based on the therapeutic outcomes of polymer-drug conjugates against breast and lung cancer. MDPI 2020-04-29 /pmc/articles/PMC7284459/ /pubmed/32365495 http://dx.doi.org/10.3390/pharmaceutics12050406 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Alven, Sibusiso
Nqoro, Xhamla
Buyana, Buhle
Aderibigbe, Blessing A.
Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer
title Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer
title_full Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer
title_fullStr Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer
title_full_unstemmed Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer
title_short Polymer-Drug Conjugate, a Potential Therapeutic to Combat Breast and Lung Cancer
title_sort polymer-drug conjugate, a potential therapeutic to combat breast and lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284459/
https://www.ncbi.nlm.nih.gov/pubmed/32365495
http://dx.doi.org/10.3390/pharmaceutics12050406
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AT buyanabuhle polymerdrugconjugateapotentialtherapeutictocombatbreastandlungcancer
AT aderibigbeblessinga polymerdrugconjugateapotentialtherapeutictocombatbreastandlungcancer

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