Cargando…
L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus
Anticancer effects of L-ascorbic acid (Vitamin C, L-AA) have been reported in various types of cancers. L-AA intake reduces breast cancer recurrence and mortality; however, the role of L-AA in the treatment of breast cancer remains poorly understood. In this study, we investigated the effect and mec...
Autores principales: | Choi, Youn Kyung, Kang, Jung-Il, Han, Sanghoon, Kim, Young Ree, Jo, Jaemin, Kang, Yong Woo, Choo, Do Ryeon, Hyun, Jin Won, Koh, Young Sang, Yoo, Eun-Sook, Kang, Hee-Kyoung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284633/ https://www.ncbi.nlm.nih.gov/pubmed/32397306 http://dx.doi.org/10.3390/nu12051351 |
Ejemplares similares
-
Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways
por: Yi, Shanyong, et al.
Publicado: (2019) -
Dimethyl fumarate abrogates striatal endoplasmic reticulum stress in experimentally induced late-stage Huntington’s disease: Focus on the IRE1α/JNK and PERK/CHOP trajectories
por: Hassab, Lina Y., et al.
Publicado: (2023) -
Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells
por: Cheng, Xiu, et al.
Publicado: (2021) -
Effect of Different Exercise Intensities on Hepatocyte Apoptosis in HFD-Induced NAFLD in Rats: The Possible Role of Endoplasmic Reticulum Stress through the Regulation of the IRE1/JNK and eIF2α/CHOP Signal Pathways
por: Ruan, Ling, et al.
Publicado: (2021) -
Melatonin promotes sirtuin 1 expression and inhibits IRE1α–XBP1S–CHOP to reduce endoplasmic reticulum stress–mediated apoptosis in chondrocytes
por: Qin, Kunpeng, et al.
Publicado: (2022)