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In Situ Gel Formation in Microporated Skin for Enhanced Topical Delivery of Niacinamide
Although used widely in cosmetic formulations, topical delivery of niacinamide (LogP = −0.35) is unfavorable by conventional means. Poly(lactide-co-glycolide) (PLGA) formulations, can undergo a sol-gel transition triggered by solvent exchange, entrapping molecules and sustaining their release. The c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284857/ https://www.ncbi.nlm.nih.gov/pubmed/32455797 http://dx.doi.org/10.3390/pharmaceutics12050472 |