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Injectable SN-38-embedded Polymeric Microparticles Promote Antitumor Efficacy against Malignant Glioma in an Animal Model

Malignant glioma (MG) is extremely aggressive and highly resistant to chemotherapeutic agents. Using electrospraying, the potent chemotherapeutic agent 7-ethyl-10-hydroxycamptothecia (SN-38) was embedded into 50:50 biodegradable poly[(d,l)-lactide-co-glycolide] (PLGA) microparticles (SMPs). The SMPs...

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Detalles Bibliográficos
Autores principales:	Tseng, Yuan-Yun, Yang, Tao-Chieh, Chen, Shu-Mei, Yang, Shun-Tai, Tang, Ya-Ling, Liu, Shih-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285024/ https://www.ncbi.nlm.nih.gov/pubmed/32456305 http://dx.doi.org/10.3390/pharmaceutics12050479

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