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Elicitation of Cluster A and Co-Receptor Binding Site Antibodies Are Required to Eliminate HIV-1 Infected Cells

HIV-1-infected individuals raise a polyclonal antibody response targeting multiple envelope glycoprotein (Env) epitopes. Interestingly, two classes of non-neutralizing CD4-induced (CD4i) antibodies, present in the majority of HIV-1-infected individuals have been described to mediate antibody-depende...

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Detalles Bibliográficos
Autores principales: Beaudoin-Bussières, Guillaume, Prévost, Jérémie, Gendron-Lepage, Gabrielle, Melillo, Bruno, Chen, Junhua, Smith III, Amos B., Pazgier, Marzena, Finzi, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285120/
https://www.ncbi.nlm.nih.gov/pubmed/32403312
http://dx.doi.org/10.3390/microorganisms8050710