Cargando…

Elicitation of Cluster A and Co-Receptor Binding Site Antibodies Are Required to Eliminate HIV-1 Infected Cells

HIV-1-infected individuals raise a polyclonal antibody response targeting multiple envelope glycoprotein (Env) epitopes. Interestingly, two classes of non-neutralizing CD4-induced (CD4i) antibodies, present in the majority of HIV-1-infected individuals have been described to mediate antibody-depende...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beaudoin-Bussières, Guillaume, Prévost, Jérémie, Gendron-Lepage, Gabrielle, Melillo, Bruno, Chen, Junhua, Smith III, Amos B., Pazgier, Marzena, Finzi, Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285120/ https://www.ncbi.nlm.nih.gov/pubmed/32403312 http://dx.doi.org/10.3390/microorganisms8050710

Ejemplares similares

Effects of gp120 Inner Domain (ID2) Immunogen Doses on Elicitation of Anti-HIV-1 Functional Fc-Effector Response to C1/C2 (Cluster A) Epitopes in Mice
por: Sherburn, Rebekah, et al.
Publicado: (2020)

Interaction of Human ACE2 to Membrane-Bound SARS-CoV-1 and SARS-CoV-2 S Glycoproteins
por: Anand, Sai Priya, et al.
Publicado: (2020)

A new flow cytometry assay to measure antibody-dependent cellular cytotoxicity against SARS-CoV-2 Spike-expressing cells
por: Beaudoin-Bussières, Guillaume, et al.
Publicado: (2021)

Incorporating the Cluster A and V1V2 Targets into a Minimal Structural Unit of the HIV-1 Envelope to Elicit a Cross-Clade Response with Potent Fc-Effector Functions
por: Sherburn, Rebekah, et al.
Publicado: (2021)

Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells
por: Richard, Jonathan, et al.
Publicado: (2021)

SARS-CoV-2 Accessory Protein ORF8 Decreases Antibody-Dependent Cellular Cytotoxicity
por: Beaudoin-Bussières, Guillaume, et al.
Publicado: (2022)

SARS-CoV-2 seroprevalence among blood donors in Québec, and analysis of symptoms associated with seropositivity: a nested case-control study
por: Lewin, Antoine, et al.
Publicado: (2021)

Temperature Influences the Interaction between SARS-CoV-2 Spike from Omicron Subvariants and Human ACE2
por: Gong, Shang Yu, et al.
Publicado: (2022)

Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity
por: Laumaea, Annemarie, et al.
Publicado: (2023)

Humoral Responses Elicited after a Fifth Dose of SARS-CoV-2 mRNA Bivalent Vaccine
por: Tauzin, Alexandra, et al.
Publicado: (2023)

A Recent SARS-CoV-2 Infection Enhances Antibody-Dependent Cellular Cytotoxicity against Several Omicron Subvariants following a Fourth mRNA Vaccine Dose
por: Beaudoin-Bussières, Guillaume, et al.
Publicado: (2023)

Waning of SARS-CoV-2 RBD antibodies in longitudinal convalescent plasma samples within 4 months after symptom onset
por: Perreault, Josée, et al.
Publicado: (2020)

HIV-1 Envelope Glycoprotein Cell Surface Localization Is Associated with Antibody-Induced Internalization
por: Anand, Sai Priya, et al.
Publicado: (2021)

Evaluation of a Commercial Culture-Free Neutralization Antibody Detection Kit for Severe Acute Respiratory Syndrome-Related Coronavirus-2 and Comparison With an Antireceptor-Binding Domain Enzyme-Linked Immunosorbent Assay
por: Papenburg, Jesse, et al.
Publicado: (2021)

Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC
por: Ding, Shilei, et al.
Publicado: (2023)

The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site
por: Prévost, Jérémie, et al.
Publicado: (2020)

Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC
por: Ding, Shilei, et al.
Publicado: (2023)

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins
por: Richard, Jonathan, et al.
Publicado: (2016)

Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity
por: Gong, Shang Yu, et al.
Publicado: (2021)

Temsavir Treatment of HIV-1-Infected Cells Decreases Envelope Glycoprotein Recognition by Broadly Neutralizing Antibodies
por: Boutin, Marianne, et al.
Publicado: (2022)

HIV-1 Vpu restricts Fc-mediated effector functions in vivo
por: Prévost, Jérémie, et al.
Publicado: (2022)

Humoral Responses Elicited by SARS-CoV-2 mRNA Vaccine in People Living with HIV
por: Marchitto, Lorie, et al.
Publicado: (2023)

A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
por: Tauzin, Alexandra, et al.
Publicado: (2021)

Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset
por: Anand, Sai Priya, et al.
Publicado: (2021)

The great escape? SARS-CoV-2 variants evading neutralizing responses
por: Prévost, Jérémie, et al.
Publicado: (2021)

Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity
por: Marchitto, Lorie, et al.
Publicado: (2023)

Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1
por: Lewis, George K., et al.
Publicado: (2015)

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
por: Beaudoin-Bussières, Guillaume, et al.
Publicado: (2022)

Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
por: Ullah, Irfan, et al.
Publicado: (2021)

Humoral immune responses against SARS-CoV-2 Spike variants after mRNA vaccination in solid organ transplant recipients
por: Tauzin, Alexandra, et al.
Publicado: (2022)

VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry
por: Ding, Shilei, et al.
Publicado: (2022)

A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses
por: Tauzin, Alexandra, et al.
Publicado: (2022)

SARS-CoV-2 Spike Expression at the Surface of Infected Primary Human Airway Epithelial Cells
por: Ding, Shilei, et al.
Publicado: (2021)

Temsavir Modulates HIV-1 Envelope Conformation by Decreasing Its Proteolytic Cleavage
por: Boutin, Marianne, et al.
Publicado: (2023)

Humoral Responses against BQ.1.1 Elicited after Breakthrough Infection and SARS-CoV-2 mRNA Vaccination
por: Tauzin, Alexandra, et al.
Publicado: (2023)

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen
por: Nayrac, Manon, et al.
Publicado: (2022)

SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses
por: Chatterjee, Debashree, et al.
Publicado: (2022)

Evolution of Anti-RBD IgG Avidity following SARS-CoV-2 Infection
por: Tauzin, Alexandra, et al.
Publicado: (2022)

Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site
por: Tolbert, William D., et al.
Publicado: (2020)

Spike recognition and neutralization of SARS-CoV-2 Omicron subvariants elicited after the third dose of mRNA vaccine
por: Tauzin, Alexandra, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lkdse6ajtldob7hsmb2fkvb0tn