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Redox-Responsive Coordination Polymers of Dopamine-Modified Hyaluronic Acid with Copper and 6-Mercaptopurine for Targeted Drug Delivery and Improvement of Anticancer Activity against Cancer Cells
Dopamine-modified hyaluronic acid (HA-DOP) was chosen as the drug carrier in this study, and Cu(2+) was selected from among Cu(2+), Zn(2+), Fe(2+), and Ca(2+) as the central atom. 6-Mercaptopurine (6-MP) was conjugated with HA through a coordination reaction. HA-DOP-copper-MP (HA-DOP-Cu-MP), a redox...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285144/ https://www.ncbi.nlm.nih.gov/pubmed/32423174 http://dx.doi.org/10.3390/polym12051132 |