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Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid
A series of semi-interpenetrating polymer network (semi-IPN) hydrogels based on N,N’-diethylacrylamide (DEA) and itaconamic acid (IAM) were synthesized by changing the molar ratio of linear copolymer P(DEA-co-IAM) and DEA monomer. Linear copolymer P(DEA-co-IAM) was introduced into a solution of DEA...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285170/ https://www.ncbi.nlm.nih.gov/pubmed/32429371 http://dx.doi.org/10.3390/polym12051139 |
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author | Tuan, Huynh Nguyen Anh Nhu, Vo Thi Thu |
author_facet | Tuan, Huynh Nguyen Anh Nhu, Vo Thi Thu |
author_sort | Tuan, Huynh Nguyen Anh |
collection | PubMed |
description | A series of semi-interpenetrating polymer network (semi-IPN) hydrogels based on N,N’-diethylacrylamide (DEA) and itaconamic acid (IAM) were synthesized by changing the molar ratio of linear copolymer P(DEA-co-IAM) and DEA monomer. Linear copolymer P(DEA-co-IAM) was introduced into a solution of DEA monomer to prepare pH-thermo dual responsive P(DEA-co-IAM)/PDEA semi-IPN hydrogels. The thermal gravimetric analysis (TGA) revealed that the semi-IPN hydrogel has a higher thermal stability than the conventional hydrogel, while the interior morphology by scanning electron microscopy (SEM) showed a porous structure with the pore sizes could be controlled by changing the ratio of linear copolymer in the obtained hydrogels. The oscillatory parallel-plate rheological measurements and compression tests demonstrated a viscoelastic behavior and superior mechanical properties of the semi-IPN hydrogels. Besides, the lower critical solution temperature (LCST) of the linear copolymers increased with the increase of IAM content in the feed, while the semi-IPN hydrogels increased LCSTs with the increase of linear copolymer content introduced. The pH-thermo dual responsive of the hydrogels was investigated using the swelling behavior in various pH and temperature conditions. Finally, the swelling and deswelling rate of the hydrogels were also studied. The results indicated that the pH-thermo dual responsive semi-IPN hydrogels were synthesized successfully and may be a potential material for biomedical, drug delivery or absorption applications. The further applications of semi-IPN hydrogels are being conducted. |
format | Online Article Text |
id | pubmed-7285170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72851702020-06-18 Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid Tuan, Huynh Nguyen Anh Nhu, Vo Thi Thu Polymers (Basel) Article A series of semi-interpenetrating polymer network (semi-IPN) hydrogels based on N,N’-diethylacrylamide (DEA) and itaconamic acid (IAM) were synthesized by changing the molar ratio of linear copolymer P(DEA-co-IAM) and DEA monomer. Linear copolymer P(DEA-co-IAM) was introduced into a solution of DEA monomer to prepare pH-thermo dual responsive P(DEA-co-IAM)/PDEA semi-IPN hydrogels. The thermal gravimetric analysis (TGA) revealed that the semi-IPN hydrogel has a higher thermal stability than the conventional hydrogel, while the interior morphology by scanning electron microscopy (SEM) showed a porous structure with the pore sizes could be controlled by changing the ratio of linear copolymer in the obtained hydrogels. The oscillatory parallel-plate rheological measurements and compression tests demonstrated a viscoelastic behavior and superior mechanical properties of the semi-IPN hydrogels. Besides, the lower critical solution temperature (LCST) of the linear copolymers increased with the increase of IAM content in the feed, while the semi-IPN hydrogels increased LCSTs with the increase of linear copolymer content introduced. The pH-thermo dual responsive of the hydrogels was investigated using the swelling behavior in various pH and temperature conditions. Finally, the swelling and deswelling rate of the hydrogels were also studied. The results indicated that the pH-thermo dual responsive semi-IPN hydrogels were synthesized successfully and may be a potential material for biomedical, drug delivery or absorption applications. The further applications of semi-IPN hydrogels are being conducted. MDPI 2020-05-16 /pmc/articles/PMC7285170/ /pubmed/32429371 http://dx.doi.org/10.3390/polym12051139 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tuan, Huynh Nguyen Anh Nhu, Vo Thi Thu Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid |
title | Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid |
title_full | Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid |
title_fullStr | Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid |
title_full_unstemmed | Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid |
title_short | Synthesis and Properties of pH-Thermo Dual Responsive Semi-IPN Hydrogels Based on N,N’-Diethylacrylamide and Itaconamic Acid |
title_sort | synthesis and properties of ph-thermo dual responsive semi-ipn hydrogels based on n,n’-diethylacrylamide and itaconamic acid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285170/ https://www.ncbi.nlm.nih.gov/pubmed/32429371 http://dx.doi.org/10.3390/polym12051139 |
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