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Tart Cherry Increases Lifespan in Caenorhabditis elegans by Altering Metabolic Signaling Pathways
Aging and healthspan are determined by both environmental and genetic factors. The insulin/insulin-like growth factor-1(IGF-1) pathway is a key mediator of aging in Caenorhabditis elegans and mammals. Specifically, DAF-2 signaling, an ortholog of human IGF, controls DAF-16/FOXO transcription factor,...
Autores principales: | Jayarathne, Shasika, Ramalingam, Latha, Edwards, Hunter, Vanapalli, Siva A., Moustaid-Moussa, Naima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285199/ https://www.ncbi.nlm.nih.gov/pubmed/32443669 http://dx.doi.org/10.3390/nu12051482 |
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