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The Action of JAK/STAT3 and BMP/HJV/SMAD Signaling Pathways on Hepcidin Suppression by Tucum-do-Cerrado in a Normal and Iron-Enriched Diets

The Brazilian savanna fruit, tucum-do-cerrado (Bactris setosa Mart.) reduces hepatic hepcidin levels. Therefore, we investigated the effect of tucum-do-cerrado on the TfR/HFE and/or BMP/HJV/SMAD and JAK/STAT pathways, in normal and excess iron conditions. Rats were treated with: control diet (CT); c...

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Detalles Bibliográficos
Autores principales: Arruda, Sandra Fernandes, Ramos, Larissa Valadares, Barbosa, Júlia Lima de Alencar, Hankins, Natália Aboudib Campos, Rodrigues, Pedro Augusto Matos, da Cunha, Marcela de Sá Barreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285201/
https://www.ncbi.nlm.nih.gov/pubmed/32456060
http://dx.doi.org/10.3390/nu12051515