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Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I(2)-Imidazoline Receptor Ligand MCR5
Behavioural and psychological symptoms of dementia (BPSD), including fear-anxiety- and depressive-like behaviour, are present in Alzheimer’s disease (AD), together with memory decline. I(2)-imidazoline receptors (I(2)-IRs) have been associated with neuropsychiatric and neurodegenerative disorders, f...
Autores principales: | Vasilopoulou, Foteini, Bagan, Andrea, Rodriguez-Arevalo, Sergio, Escolano, Carmen, Griñán-Ferré, Christian, Pallàs, Mercè |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285228/ https://www.ncbi.nlm.nih.gov/pubmed/32456135 http://dx.doi.org/10.3390/pharmaceutics12050475 |
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