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A Selective Serotonin Reuptake Inhibitor, a Proton Pump Inhibitor, and Two Calcium Channel Blockers Inhibit Candida albicans Biofilms

Biofilms formed by the human fungal pathogen Candida albicans are naturally resistant to many of the antifungal agents commonly used in the clinic. We screened a library containing 1600 clinically tested drug compounds to identify compounds that inhibit C. albicans biofilm formation. The compounds t...

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Detalles Bibliográficos
Autores principales: Nobile, Clarissa J., Ennis, Craig L., Hartooni, Nairi, Johnson, Alexander D., Lohse, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285287/
https://www.ncbi.nlm.nih.gov/pubmed/32443498
http://dx.doi.org/10.3390/microorganisms8050756