Cargando…
The Crimean-Congo Hemorrhagic Fever Virus NSm Protein Is Dispensable for Growth In Vitro and Disease in Ifnar(-/-) Mice
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tri-segmented, tick-borne nairovirus that causes disease of ranging severity in humans. The CCHFV M segment encodes a complex glycoprotein precursor (GPC) that undergoes extensive endoproteolytic cleavage, giving rise to two structural proteins (Gn...
Autores principales: | Welch, Stephen R., Scholte, Florine E. M., Spengler, Jessica R., Ritter, Jana M., Coleman-McCray, JoAnn D., Harmon, Jessica R., Nichol, Stuart T., Zaki, Sherif R., Spiropoulou, Christina F., Bergeron, Eric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285326/ https://www.ncbi.nlm.nih.gov/pubmed/32455700 http://dx.doi.org/10.3390/microorganisms8050775 |
Ejemplares similares
-
Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar(-/-) mice
por: Welch, Stephen R., et al.
Publicado: (2019) -
Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice
por: Scholte, Florine E. M., et al.
Publicado: (2019) -
Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection
por: Scholte, Florine E. M., et al.
Publicado: (2019) -
Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus
por: Zivcec, Marko, et al.
Publicado: (2016) -
Crimean-Congo Hemorrhagic Fever in Humanized Mice Reveals Glial Cells as Primary Targets of Neurological Infection
por: Spengler, Jessica R, et al.
Publicado: (2017)