Cargando…

Evaluation of Product Distribution in Chemostat and Batch Fermentation in Lactic Acid-Producing Komagataella phaffii Strains Utilizing Glycerol as Substrate

Lactic acid is the monomeric unit of polylactide (PLA), a bioplastic widely used in the packaging, automotive, food, and pharmaceutical industries. Previously, the yeast Komagataella phaffii was genetically modified for the production of lactate from glycerol. For this, the bovine L-lactate dehydrog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tamires Moreira Melo, Nadielle, Pontes, Gabriela Coimbra, Procópio, Dielle Pierotti, de Gois e Cunha, Gabriel Caetano, Eliodório, Kevy Pontes, Costa Paes, Hugo, Basso, Thiago Olitta, Parachin, Nádia Skorupa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285341/ https://www.ncbi.nlm.nih.gov/pubmed/32455925 http://dx.doi.org/10.3390/microorganisms8050781

Ejemplares similares

Loss of a Functional Mitochondrial Pyruvate Carrier in Komagataella phaffii Does Not Improve Lactic Acid Production from Glycerol in Aerobic Cultivation
por: de Oliveira Junqueira, Ana Caroline, et al.
Publicado: (2023)

Physiology of Saccharomyces cerevisiae during growth on industrial sugar cane molasses can be reproduced in a tailor-made defined synthetic medium
por: Eliodório, Kevy Pontes, et al.
Publicado: (2023)

What makes Komagataella phaffii non-conventional?
por: Ata, Özge, et al.
Publicado: (2021)

Identification and characterization of the Komagataella phaffii mating pheromone genes
por: Heistinger, Lina, et al.
Publicado: (2018)

A subcellular proteome atlas of the yeast Komagataella phaffii
por: Valli, Minoska, et al.
Publicado: (2020)

Komagataella phaffii as Emerging Model Organism in Fundamental Research
por: Bernauer, Lukas, et al.
Publicado: (2021)

Effect of Methionine on Gene Expression in Komagataella phaffii Cells
por: Ianshina, Tatiana, et al.
Publicado: (2023)

Industrial Production of Proteins with Pichia pastoris—Komagataella phaffii
por: Barone, Giovanni Davide, et al.
Publicado: (2023)

Effect of Pyruvate Decarboxylase Knockout on Product Distribution Using Pichia pastoris (Komagataella phaffii) Engineered for Lactic Acid Production
por: Melo, Nadiele T. M., et al.
Publicado: (2018)

Pseudohyphal differentiation in Komagataella phaffii: investigating the FLO gene family
por: De, Sonakshi, et al.
Publicado: (2020)

Histidine is essential for growth of Komagataella phaffii cultured in YPA medium
por: Gupta, Aditi, et al.
Publicado: (2022)

Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
por: Albacar, Marcel, et al.
Publicado: (2023)

Alternative PCR-Based Approaches for Generation of Komagataella phaffii Strains
por: Makeeva, Anastasiya, et al.
Publicado: (2023)

Modulation of acetate utilization in Komagataella phaffii by metabolic engineering of tolerance and metabolism
por: Xu, Qin, et al.
Publicado: (2019)

Advances in Cell Engineering of the Komagataella phaffii Platform for Recombinant Protein Production
por: Bustos, Cristina, et al.
Publicado: (2022)

Evaluation of reference genes for transcript analyses in Komagataella phaffii (Pichia pastoris)
por: Besleaga, Mihail, et al.
Publicado: (2023)

Correction: Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
por: Albacar, Marcel, et al.
Publicado: (2023)

Use of an on/off tetracycline riboswitch to control protein production in Komagataella phaffii
por: Vieira, Igor Patrick Vasconcelos, et al.
Publicado: (2023)

Process development for the continuous production of heterologous proteins by the industrial yeast, Komagataella phaffii
por: Cankorur‐Cetinkaya, Ayca, et al.
Publicado: (2018)

Multicopy plasmid integration in Komagataella phaffii mediated by a defective auxotrophic marker
por: Betancur, Maritza Ocampo, et al.
Publicado: (2017)

Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii
por: Alva, Troy R., et al.
Publicado: (2021)

Transcriptome Analysis Unveils the Effects of Proline on Gene Expression in the Yeast Komagataella phaffii
por: Rumyantsev, Andrey, et al.
Publicado: (2021)

Regulation of Peroxisome Homeostasis by Post-Translational Modification in the Methylotrophic Yeast Komagataella phaffii
por: Ohsawa, Shin, et al.
Publicado: (2022)

Heterologous Expression of Extracellular Proteinase pAsPs of Aspergillus pseudotamarii in Komagataella phaffii
por: Zadorozhny, Andrey Valentinovich, et al.
Publicado: (2022)

Recombinant Inga Laurina Trypsin Inhibitor (ILTI) Production in Komagataella Phaffii Confirms Its Potential Anti-Biofilm Effect and Reveals an Anti-Tumoral Activity
por: Carneiro, Fábio C., et al.
Publicado: (2018)

Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation
por: Heistinger, Lina, et al.
Publicado: (2017)

L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
por: Freitas, Marcela, et al.
Publicado: (2022)

Role of Dissimilative Pathway of Komagataella phaffii (Pichia pastoris): Formaldehyde Toxicity and Energy Metabolism
por: Berrios, Julio, et al.
Publicado: (2022)

Heterologous Expression of Xylanase xAor from Aspergillus oryzae in Komagataella phaffii T07
por: Zadorozhny, Andrey Valentinovich, et al.
Publicado: (2022)

Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications
por: Swichkow, Chantle Reiko, et al.
Publicado: (2022)

Centromeres of the Yeast Komagataella phaffii (Pichia pastoris) Have a Simple Inverted-Repeat Structure
por: Coughlan, Aisling Y., et al.
Publicado: (2016)

A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
por: Ata, Özge, et al.
Publicado: (2018)

Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)
por: Braun-Galleani, Stephanie, et al.
Publicado: (2019)

Two homologs of the Cat8 transcription factor are involved in the regulation of ethanol utilization in Komagataella phaffii
por: Barbay, Diane, et al.
Publicado: (2021)

Applying the auxin-based degron system for the inducible, reversible and complete protein degradation in Komagataella phaffii
por: Lehmayer, Leonie, et al.
Publicado: (2022)

Coordinate regulation of methanol utilization pathway genes of Komagataella phaffii by transcription factors and chromatin modifiers
por: Gupta, Aditi, et al.
Publicado: (2022)

Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid
por: Àvila-Cabré, Sílvia, et al.
Publicado: (2023)

Transcriptomic Analysis of Pichia pastoris (Komagataella phaffii) GS115 During Heterologous Protein Production Using a High-Cell-Density Fed-Batch Cultivation Strategy
por: Zhang, Chengbo, et al.
Publicado: (2020)

Metabolic modeling to identify engineering targets for Komagataella phaffii: The effect of biomass composition on gene target identification
por: Cankorur‐Cetinkaya, Ayca, et al.
Publicado: (2017)

Construction and characterization of centromeric plasmids for Komagataella phaffii using a color-based plasmid stability assay
por: Piva, Luiza Cesca, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j1uuk4tvlf0659e94vetse140k