Autoimmune Mechanisms of Interferon Hypersensitivity and Neurodegenerative Diseases: Down Syndrome

Down syndrome (DS), also known as trisomy 21 (T21), is associated with interferon (IFN) hypersensitivity, as well as predilections for Alzheimer's dementia (AD) and various autoimmune diseases. IFN-α and IFN-γ receptors are encoded on chromosome 21 (Ch21). It remains unclear how other Ch21 gene...

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Detalles Bibliográficos
Autores principales: Jagadeesh, Ashraya, Maroun, Leonard E., Van Es, Lisa M., Millis, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285398/
https://www.ncbi.nlm.nih.gov/pubmed/32566271
http://dx.doi.org/10.1155/2020/6876920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285398/
https://www.ncbi.nlm.nih.gov/pubmed/32566271
http://dx.doi.org/10.1155/2020/6876920

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