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Reduced frequency and functional defects of CD4(+)CD25(high)CD127(low/−) regulatory T cells in patients with unexplained recurrent spontaneous abortion

BACKGROUND: Unexplained recurrent spontaneous abortion (URSA) is defined as two or more consecutive pregnancy losses, generally of unknown cause; it is related to a failure of fetal–maternal immunological tolerance. Regulatory T cells (Tregs) exert immunosuppressive effects, which are essential to m...

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Detalles Bibliográficos
Autores principales:	Luo, Li, Zeng, Xun, Huang, Zhongying, Luo, Shan, Qin, Lang, Li, Shangwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285476/ https://www.ncbi.nlm.nih.gov/pubmed/32522204 http://dx.doi.org/10.1186/s12958-020-00619-7

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