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ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals

BACKGROUND: Acylphosphatase 2 (ACYP2) is involved in cell differentiation, energy metabolism and hydrolysis of intracellular ion pump. It has been reported as a negative regulator in leukemia and a positive regulator in colon cancer, respectively. However, its biological role in glioma remains total...

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Detalles Bibliográficos
Autores principales: Li, Mengdan, Ruan, Banjun, Wei, Jing, Yang, Qi, Chen, Mingwei, Ji, Meiju, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285537/
https://www.ncbi.nlm.nih.gov/pubmed/32517717
http://dx.doi.org/10.1186/s13046-020-01607-w