Cargando…

Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer’s disease pathology

BACKGROUND: Heme and iron homeostasis is perturbed in Alzheimer’s disease (AD); therefore, the aim of the study was to examine the levels and association of heme with iron-binding plasma proteins in cognitively normal (CN), mild cognitive impairment (MCI), and AD individuals from the Australian Imag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ashraf, Azhaar, Ashton, Nicholas J., Chatterjee, Pratishtha, Goozee, Kathryn, Shen, Kaikai, Fripp, Jurgen, Ames, David, Rowe, Christopher, Masters, Colin L., Villemagne, Victor, Hye, Abdul, Martins, Ralph N., So, Po-Wah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285604/ https://www.ncbi.nlm.nih.gov/pubmed/32517787 http://dx.doi.org/10.1186/s13195-020-00634-1

Ejemplares similares

Low Cerebrospinal Fluid Levels of Hemopexin Are Associated With Increased Alzheimer's Pathology, Hippocampal Hypometabolism, and Cognitive Decline
por: Ashraf, Azhaar A., et al.
Publicado: (2020)

Spotlight on Ferroptosis: Iron-Dependent Cell Death in Alzheimer’s Disease
por: Ashraf, Azhaar, et al.
Publicado: (2020)

Higher Coffee Consumption Is Associated With Slower Cognitive Decline and Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From the Australian Imaging, Biomarkers, and Lifestyle Study
por: Gardener, Samantha L., et al.
Publicado: (2021)

Hemopexin and Cancer
por: Fiorito, Veronica, et al.
Publicado: (2022)

The Aging of Iron Man
por: Ashraf, Azhaar, et al.
Publicado: (2018)

Co-precipitation molecules hemopexin and transferrin may be key molecules for fibrillogenesis in TTR V30M amyloidogenesis
por: Ohta, Mika, et al.
Publicado: (2017)

Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake
por: Fiorito, Veronica, et al.
Publicado: (2013)

Plasma Glial Fibrillary Acidic Protein Is Associated with (18)F-SMBT-1 PET: Two Putative Astrocyte Reactivity Biomarkers for Alzheimer’s Disease
por: Chatterjee, Pratishtha, et al.
Publicado: (2023)

Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis
por: Ashraf, Azhaar, et al.
Publicado: (2020)

A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer’s disease
por: Ashton, Nicholas J., et al.
Publicado: (2019)

MR-Less Surface-Based Amyloid Assessment Based on (11)C PiB PET
por: Zhou, Luping, et al.
Publicado: (2014)

Low Cerebrospinal Fluid Levels of Melanotransferrin Are Associated With Conversion of Mild Cognitively Impaired Subjects to Alzheimer’s Disease
por: Ashraf, Azhaar, et al.
Publicado: (2019)

Transferrin-binding protein complex is the receptor for transferrin uptake in Trypanosoma brucei
Publicado: (1995)

Hemopexin as an Inhibitor of Hemolysis-Induced Complement Activation
por: Poillerat, Victoria, et al.
Publicado: (2020)

New Insights into Hemopexin-Binding to Hemin and Hemoglobin
por: Lechuga, Guilherme C., et al.
Publicado: (2022)

Amyloid-Related Memory Decline in Preclinical Alzheimer’s Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months
por: Thai, Christine, et al.
Publicado: (2015)

Pattern of Altered Plasma Elemental Phosphorus, Calcium, Zinc, and Iron in Alzheimer’s Disease
por: Ashraf, Azhaar, et al.
Publicado: (2019)

Publisher Correction: Pattern of Altered Plasma Elemental Phosphorus, Calcium, Zinc, and Iron in Alzheimer’s Disease
por: Ashraf, Azhaar, et al.
Publicado: (2019)

Retinal vascular and structural changes are associated with amyloid burden in the elderly: ophthalmic biomarkers of preclinical Alzheimer’s disease
por: Golzan, S.Mojtaba, et al.
Publicado: (2017)

Relationship between amyloid and tau levels and its impact on tau spreading
por: Doré, Vincent, et al.
Publicado: (2021)

Rates of regional tau accumulation in ageing and across the Alzheimer's disease continuum: an AIBL (18)F-MK6240 PET study
por: Krishnadas, Natasha, et al.
Publicado: (2023)

A Role for Hemopexin in Oligodendrocyte Differentiation and Myelin Formation
por: Morello, Noemi, et al.
Publicado: (2011)

Association between haptoglobin, hemopexin and mortality in adults with sepsis
por: Janz, David R, et al.
Publicado: (2013)

Data demonstrating the anti-oxidant role of hemopexin in the heart
por: Ingoglia, Giada, et al.
Publicado: (2017)

Human Plasma and Recombinant Hemopexins: Heme Binding Revisited
por: Karnaukhova, Elena, et al.
Publicado: (2021)

Effect of BDNF Val66Met on Memory Decline and Hippocampal Atrophy in Prodromal Alzheimer’s Disease: A Preliminary Study
por: Lim, Yen Ying, et al.
Publicado: (2014)

Uptake of Non-Transferrin Iron by Erythroid Cells
por: Prus, Eugenia, et al.
Publicado: (2011)

Amyloid β–associated cognitive decline in the absence of clinical disease progression and systemic illness
por: Harrington, Karra D., et al.
Publicado: (2017)

Alterations in erythrocyte fatty acid composition in preclinical Alzheimer’s disease
por: Goozee, Kathryn, et al.
Publicado: (2017)

Hemopexin induces neuroprotection in the rat subjected to focal cerebral ischemia
por: Dong, Beibei, et al.
Publicado: (2013)

Hemopexin in severe inflammation and infection: mouse models and human diseases
por: Lin, Tian, et al.
Publicado: (2015)

Hemopexin Modulates Expression of Complement Regulatory Proteins in Rat Glomeruli
por: Detsika, Maria G., et al.
Publicado: (2021)

Involvement of Hemopexin in the Pathogenesis of Proteinuria in Children with Idiopathic Nephrotic Syndrome
por: Pukajło-Marczyk, Agnieszka, et al.
Publicado: (2021)

Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice
por: Liu, Jing, et al.
Publicado: (2022)

Cerebrospinal Fluid Neurofilament Light Predicts Risk of Dementia Onset in Cognitively Healthy Individuals and Rate of Cognitive Decline in Mild Cognitive Impairment: A Prospective Longitudinal Study
por: Dhiman, Kunal, et al.
Publicado: (2022)

Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-β Load
por: Chatterjee, Pratishtha, et al.
Publicado: (2020)

APOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease
por: Lim, Y Y, et al.
Publicado: (2015)

Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer’s Disease
por: Lim, Wei Ling Florence, et al.
Publicado: (2020)

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles
por: Higashisaka, Kazuma, et al.
Publicado: (2012)

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders
por: Smith, Ann, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0s3itunrb1flaeptjudgddjg78