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Extracellular vesicle-encapsulated miR-22-3p from bone marrow mesenchymal stem cell promotes osteogenic differentiation via FTO inhibition

BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) exhibit the capacity to self-renew and differentiate into multi-lineage cell types, including osteoblasts, which are crucial regulators of fracture healing. Thus, this study aims to investigate the effect of microRNA (miR)-22-3p from BMSC-derive...

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Detalles Bibliográficos
Autores principales: Zhang, Xueliang, Wang, Yongping, Zhao, Haiyan, Han, Xingwen, Zhao, Tong, Qu, Peng, Li, Guangjie, Wang, Wenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285613/
https://www.ncbi.nlm.nih.gov/pubmed/32522250
http://dx.doi.org/10.1186/s13287-020-01707-6