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Extracellular vesicle-encapsulated miR-22-3p from bone marrow mesenchymal stem cell promotes osteogenic differentiation via FTO inhibition
BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) exhibit the capacity to self-renew and differentiate into multi-lineage cell types, including osteoblasts, which are crucial regulators of fracture healing. Thus, this study aims to investigate the effect of microRNA (miR)-22-3p from BMSC-derive...
Autores principales: | Zhang, Xueliang, Wang, Yongping, Zhao, Haiyan, Han, Xingwen, Zhao, Tong, Qu, Peng, Li, Guangjie, Wang, Wenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285613/ https://www.ncbi.nlm.nih.gov/pubmed/32522250 http://dx.doi.org/10.1186/s13287-020-01707-6 |
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