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Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits

Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and neurodegeneration. Immunosuppressive treatments can modify the disease course but do not effectively promote remyelination or prevent long term neurodegeneration. As a novel approach to mitigate chronic stag...

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Detalles Bibliográficos
Autores principales: Sullivan, Genevieve M., Knutsen, Andrew K., Peruzzotti-Jametti, Luca, Korotcov, Alexandru, Bosomtwi, Asamoah, Dardzinski, Bernard J., Bernstock, Joshua D., Rizzi, Sandra, Edenhofer, Frank, Pluchino, Stefano, Armstrong, Regina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285785/
https://www.ncbi.nlm.nih.gov/pubmed/32517808
http://dx.doi.org/10.1186/s40478-020-00960-3