Cargando…

Signal transducer and activator of transcription 6 as a target in colon cancer therapy

Signal transducer and activator of transcription 6 (STAT6) is a member of the STAT family of proteins that serve key roles in the initiation of tumorigenesis and malignant transformation. STAT6 is highly expressed in several types of cancer, including breast, pancreatic, prostate and colorectal canc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Delgado-Ramirez, Yael, Colly, Vaneesa, Gonzalez, Giovanni Villanueva, Leon-Cabrera, Sonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285805/ https://www.ncbi.nlm.nih.gov/pubmed/32565970 http://dx.doi.org/10.3892/ol.2020.11614

Ejemplares similares

Signal Transducer and Activator of Transcription 6 Is Essential in the Induction of Contact Hypersensitivity
por: Yokozeki, Hiroo, et al.
Publicado: (2000)

Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis
por: Kurosaka, Mitsutoshi, et al.
Publicado: (2021)

An Association Study of the Signal Transducer and Activator of Transcription 6 Gene With Periodic Psychosis
por: Kawashige, Seiya, et al.
Publicado: (2008)

Signal Transducer and Activator of Transcription 4 in Liver Diseases
por: Wang, Yan, et al.
Publicado: (2015)

Signal Transducer and Activator of Transcription 3 in Liver Diseases: A Novel Therapeutic Target
por: Wang, Hua, et al.
Publicado: (2011)

Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6
por: Weaver, Amanda M, et al.
Publicado: (2007)

Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development
por: Healey, Gareth D, et al.
Publicado: (2010)

Bazedoxifene exhibits growth suppressive activity by targeting interleukin‐6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma
por: Ma, Haiyan, et al.
Publicado: (2019)

Activation-Induced Inhibition of Interleukin 6–Mediated T Cell Survival and Signal Transducer and Activator of Transcription 1 Signaling
por: Teague, T. Kent, et al.
Publicado: (2000)

Mutations in the signal transducer and activator of transcription family of genes in cancer
por: Shahmarvand, Nahid, et al.
Publicado: (2018)

Prognostic values of signal transducers activators of transcription in gastric cancer
por: Zhang, Yujie, et al.
Publicado: (2019)

Suppression of Signal Transducer and Activator of Transcription 3–Dependent B Lymphocyte Terminal Differentiation by Bcl-6
por: Reljic, Rajko, et al.
Publicado: (2000)

Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy
por: Dufait, Inès, et al.
Publicado: (2016)

Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer
por: Furth, Priscilla A, et al.
Publicado: (2011)

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
por: Arora, Loukik, et al.
Publicado: (2018)

Interleukin-27 decreases ghrelin production through signal transducer and activator of transcription 3—mechanistic target of rapamycin signaling
por: Zhang, Heng, et al.
Publicado: (2020)

Abrogation of Bronchial Eosinophilic Inflammation and Airway Hyperreactivity in Signal Transducers and Activators of Transcription (STAT)6-deficient Mice
por: Akimoto, Toshihiko, et al.
Publicado: (1998)

Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma
por: Litonjua, Augusto A, et al.
Publicado: (2005)

Signal Transducers and Activators of Transcription (STAT) Family Members in Helminth Infections
por: Becerra-Díaz, Mireya, et al.
Publicado: (2011)

Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development
por: Bromberg, Jacqueline
Publicado: (2000)

Signal transducer and activator of transcription 3 mutation with invasive eosinophilic disease
por: Crosby, Kara, et al.
Publicado: (2012)

Signal transducer and activator of transcription-1 localizes to the mitochondria and modulates mitophagy
por: Bourke, Lauren T, et al.
Publicado: (2013)

Immunohistological Analysis of the Jun Family and the Signal Transducers and Activators of Transcription in Thymus
por: Papoudou-Bai, Alexandra, et al.
Publicado: (2015)

The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis
por: Gao, Peng, et al.
Publicado: (2017)

The prognostic values of signal transducers activators of transcription family in ovarian cancer
por: Li, Saisai, et al.
Publicado: (2017)

Mechanisms of Viral Degradation of Cellular Signal Transducer and Activator of Transcription 2
por: Barik, Sailen
Publicado: (2022)

Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation
por: Ortmann, Robert A, et al.
Publicado: (2000)

MicroRNA-361-5p suppresses cancer progression by targeting signal transducer and activator of transcription 6 in non-small cell lung cancer
por: MA, YUEFENG, et al.
Publicado: (2015)

Therapeutic Targeting of STAT3 (Signal Transducers and Activators of Transcription 3) Pathway Inhibits Experimental Autoimmune Uveitis
por: Yu, Cheng-Rong, et al.
Publicado: (2012)

STAT6 Is Critical for the Induction of Regulatory T Cells In Vivo Controlling the Initial Steps of Colitis-Associated Cancer
por: Delgado-Ramirez, Yael, et al.
Publicado: (2021)

Interleukin-6 induces malignant transformation of rat mesenchymal stem cells in association with enhanced signaling of signal transducer and activator of transcription 3
por: Cui, Xiangrong, et al.
Publicado: (2014)

Anticancer Activity of Tubulosine through Suppression of Interleukin-6-Induced Janus Kinase 2/Signal Transducer and Activation of Transcription 3 Signaling
por: Kim, Byung-Hak, et al.
Publicado: (2019)

Pivotal Role of Signal Transducer and Activator of Transcription (Stat)4 and Stat6 in the Innate Immune Response during Sepsis
por: Matsukawa, Akihiro, et al.
Publicado: (2001)

Signal Transducer and Activator of Transcription 3 for the Differentiation of Hepatocellular Carcinoma from Cirrhosis
por: Li, Yan-Ping, et al.
Publicado: (2017)

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses
por: Deenick, Elissa K., et al.
Publicado: (2018)

Prognostic roles of signal transducers and activators of transcription family in human breast cancer
por: Wang, Shuntao, et al.
Publicado: (2018)

Role of Janus kinase 1 and signal transducer and activator of transcription 3 in vitiligo
por: Samaka, Rehab M, et al.
Publicado: (2019)

Upregulation of signal transducer and activator of transcription 3 in dogs with chronic inflammatory enteropathies
por: Manz, Anita, et al.
Publicado: (2021)

Signal transducer and activator of transcription 3 (STAT3) signaling in retinal pigment epithelium cells
por: Patel, Amit K, et al.
Publicado: (2013)

Signal Transducer and Activator of Transcription Factor 6 (Stat6)-deficient Mice Are Protected from Antigen-induced Airway Hyperresponsiveness and Mucus Production
por: Kuperman, Douglas, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_sj71k2btjidao4pe531fpmabcu