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ASR488, a novel small molecule, activates an mRNA binding protein, CPEB1, and inhibits the growth of bladder cancer

Due to a lack of mechanistic insights, muscle-invasive bladder cancer (MIBC) remains incurable and is one of the most lethal types of cancer in the United States. The present study investigated changes in the molecular signatures of MIBC cells (TCCSUP and HT1376) after treatment with a novel small m...

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Detalles Bibliográficos
Autores principales: Tyagi, Ashish, Kolluru, Venkatesh, Chandrasekaran, Balaji, Saran, Uttara, Sharma, Arun K., Ankem, Murali K., Damodaran, Chendil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285857/
https://www.ncbi.nlm.nih.gov/pubmed/32566012
http://dx.doi.org/10.3892/ol.2020.11593