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Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2

Mechanical loading-related strains trigger bone formation by osteoblasts while suppressing resorption by osteoclasts, uncoupling the processes of formation and resorption. Osteocytes may orchestrate this process in part by secreting sclerostin (SOST), which inhibits osteoblasts, and expressing recep...

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Detalles Bibliográficos
Autores principales:	Galea, Gabriel L., Paradise, Christopher R., Meakin, Lee B., Camilleri, Emily T., Taipaleenmaki, Hanna, Stein, Gary S., Lanyon, Lance E., Price, Joanna S., van Wijnen, Andre J., Dudakovic, Amel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285908/ https://www.ncbi.nlm.nih.gov/pubmed/32550554 http://dx.doi.org/10.1016/j.gene.2020.100027

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