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Glucose and TNF enhance expression of TNF and IL1B, and histone H3 acetylation and K4/K36 methylation, in juvenile macrophage cells

Hyperglycemia activates innate leukocytes such as monocytes and induces pro-inflammatory cytokine expression, resulting in increased monocyte adhesion to aortic endothelial cells. In this study, we investigated whether high glucose and/or tumor necrosis factor (TNF) would enhance pro-inflammatory cy...

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Detalles Bibliográficos
Autores principales:	Honma, Kazue, Machida, Chie, Mochizuki, Kazuki, Goda, Toshinao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285958/ https://www.ncbi.nlm.nih.gov/pubmed/32550560 http://dx.doi.org/10.1016/j.gene.2020.100034

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