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Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka

The Ceylon krait (Bungarus ceylonicus) is a highly venomous elapid snake endemic to Sri Lanka. Its bites are rare and only seven reports are found in the literature. Therefore, the clinical manifestations and natural history of envenoming of Ceylon krait are not well studied yet. Neuroparalysis is t...

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Autores principales: Kularatne, S.A.M., Colombage, Anuradha, de Silva, Anslem, Weerasinghe, Vajira, Rathnayaka, R.M.M.K. Namal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286062/
https://www.ncbi.nlm.nih.gov/pubmed/32550572
http://dx.doi.org/10.1016/j.toxcx.2019.100015
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author Kularatne, S.A.M.
Colombage, Anuradha
de Silva, Anslem
Weerasinghe, Vajira
Rathnayaka, R.M.M.K. Namal
author_facet Kularatne, S.A.M.
Colombage, Anuradha
de Silva, Anslem
Weerasinghe, Vajira
Rathnayaka, R.M.M.K. Namal
author_sort Kularatne, S.A.M.
collection PubMed
description The Ceylon krait (Bungarus ceylonicus) is a highly venomous elapid snake endemic to Sri Lanka. Its bites are rare and only seven reports are found in the literature. Therefore, the clinical manifestations and natural history of envenoming of Ceylon krait are not well studied yet. Neuroparalysis is the main clinical manifestation of their bites. We report two cases of proven Ceylon krait bites of two young snake keepers working in a serpentarium. They developed acute neuroparalysis, abdominal pain and a period of amnesia. The first patient developed myalgia and increased level of serum creatine kinase suggestive of rhabdomyolysis. One was treated with Indian polyvalent antivenom and both recovered with some long-lasting clinical disabilities namely impairment of sensation of the bitten arm and persistent refraction errors in the eyes in the first patient. The second patient had persistent marked nystagmus.
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spelling pubmed-72860622020-06-16 Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka Kularatne, S.A.M. Colombage, Anuradha de Silva, Anslem Weerasinghe, Vajira Rathnayaka, R.M.M.K. Namal Toxicon X Mini-review The Ceylon krait (Bungarus ceylonicus) is a highly venomous elapid snake endemic to Sri Lanka. Its bites are rare and only seven reports are found in the literature. Therefore, the clinical manifestations and natural history of envenoming of Ceylon krait are not well studied yet. Neuroparalysis is the main clinical manifestation of their bites. We report two cases of proven Ceylon krait bites of two young snake keepers working in a serpentarium. They developed acute neuroparalysis, abdominal pain and a period of amnesia. The first patient developed myalgia and increased level of serum creatine kinase suggestive of rhabdomyolysis. One was treated with Indian polyvalent antivenom and both recovered with some long-lasting clinical disabilities namely impairment of sensation of the bitten arm and persistent refraction errors in the eyes in the first patient. The second patient had persistent marked nystagmus. Elsevier 2019-10-02 /pmc/articles/PMC7286062/ /pubmed/32550572 http://dx.doi.org/10.1016/j.toxcx.2019.100015 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Mini-review
Kularatne, S.A.M.
Colombage, Anuradha
de Silva, Anslem
Weerasinghe, Vajira
Rathnayaka, R.M.M.K. Namal
Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka
title Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka
title_full Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka
title_fullStr Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka
title_full_unstemmed Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka
title_short Acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in Ceylon krait (Bungarus ceylonicus) bites: Two authentic cases from a serpentarium in Sri Lanka
title_sort acute neuromuscular paralysis, rhabdomyolysis and long lasting neurological deficits in ceylon krait (bungarus ceylonicus) bites: two authentic cases from a serpentarium in sri lanka
topic Mini-review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286062/
https://www.ncbi.nlm.nih.gov/pubmed/32550572
http://dx.doi.org/10.1016/j.toxcx.2019.100015
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