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Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI)
Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands. Alkaloids and steroids showed characteristic di...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286094/ https://www.ncbi.nlm.nih.gov/pubmed/32550588 http://dx.doi.org/10.1016/j.toxcx.2020.100033 |
| _version_ | 1783544817246011392 |
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| author | Mailho-Fontana, Pedro L. Porcari, Andreia M. Eberlin, Marcos N. Jared, Carlos Antoniazzi, Marta Maria Pimenta, Daniel C. Sciani, Juliana M. |
| author_facet | Mailho-Fontana, Pedro L. Porcari, Andreia M. Eberlin, Marcos N. Jared, Carlos Antoniazzi, Marta Maria Pimenta, Daniel C. Sciani, Juliana M. |
| author_sort | Mailho-Fontana, Pedro L. |
| collection | PubMed |
| description | Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands. Alkaloids and steroids showed characteristic distribution and intensity within the glands and were also present at lower levels on the skin surface. A comprehensive overview of toxins distribution in toads’ skin might help to understand their full biological role within the amphibians. |
| format | Online Article Text |
| id | pubmed-7286094 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-72860942020-06-16 Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) Mailho-Fontana, Pedro L. Porcari, Andreia M. Eberlin, Marcos N. Jared, Carlos Antoniazzi, Marta Maria Pimenta, Daniel C. Sciani, Juliana M. Toxicon X Venomics at the crossroads between ecological and clinical toxinology, Edited by: Dr. Juan Calvete, Dr.Jose Maria Gutiérrez and Dr. Cleópatra A.S. Caldeira Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands. Alkaloids and steroids showed characteristic distribution and intensity within the glands and were also present at lower levels on the skin surface. A comprehensive overview of toxins distribution in toads’ skin might help to understand their full biological role within the amphibians. Elsevier 2020-04-28 /pmc/articles/PMC7286094/ /pubmed/32550588 http://dx.doi.org/10.1016/j.toxcx.2020.100033 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Venomics at the crossroads between ecological and clinical toxinology, Edited by: Dr. Juan Calvete, Dr.Jose Maria Gutiérrez and Dr. Cleópatra A.S. Caldeira Mailho-Fontana, Pedro L. Porcari, Andreia M. Eberlin, Marcos N. Jared, Carlos Antoniazzi, Marta Maria Pimenta, Daniel C. Sciani, Juliana M. Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) |
| title | Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) |
| title_full | Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) |
| title_fullStr | Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) |
| title_full_unstemmed | Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) |
| title_short | Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI) |
| title_sort | distribution of major toxins in rhinella marina parotoid macroglands using desorption-electrospray-ionization mass spectrometry imaging (desi-msi) |
| topic | Venomics at the crossroads between ecological and clinical toxinology, Edited by: Dr. Juan Calvete, Dr.Jose Maria Gutiérrez and Dr. Cleópatra A.S. Caldeira |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286094/ https://www.ncbi.nlm.nih.gov/pubmed/32550588 http://dx.doi.org/10.1016/j.toxcx.2020.100033 |
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