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Tideglusib, a prospective alternative to nonoxynol-9 contraceptive
OBJECTIVES: We aimed to evaluate the antifertility activity and vaginal irritation effects of tideglusib in vivo using rabbit models and to evaluate the cytotoxical effects of tideglusib to sperm, vaginal cells and vaginal bacteria (L. acidophilus) in vitro. STUDY DESIGN: We treated female rabbits w...
Autores principales: | Chen, Zhiting, Shu, Niyan, Wang, Yuzhu, Yang, Yiting, Shao, Zhiyu, Tian, Fang, Xia, Minjie, Wang, Zhikai, Wang, Xin, Feng, Xing, Huang, Xianliang, Li, Weihua, Yu, Heguo, Diao, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286178/ https://www.ncbi.nlm.nih.gov/pubmed/32550526 http://dx.doi.org/10.1016/j.conx.2019.100007 |
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