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Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities

The COVID-19 pandemic affected many activities in the healthcare system including oncology drug development. Clinical trial recruitment was temporary halted in many centres to reduce patients and healthcare workers’ potential exposure to the virus. Conversely, to continue offering treatments for pat...

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Detalles Bibliográficos
Autores principales: Fontana, Elisa, Arkenau, Hendrik-Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286270/
https://www.ncbi.nlm.nih.gov/pubmed/32544543
http://dx.doi.org/10.1016/j.ctrv.2020.102047
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author Fontana, Elisa
Arkenau, Hendrik-Tobias
author_facet Fontana, Elisa
Arkenau, Hendrik-Tobias
author_sort Fontana, Elisa
collection PubMed
description The COVID-19 pandemic affected many activities in the healthcare system including oncology drug development. Clinical trial recruitment was temporary halted in many centres to reduce patients and healthcare workers’ potential exposure to the virus. Conversely, to continue offering treatments for patients already on effective therapies, multiple actions were timely put in place, resulting in simplification of trial-related procedures for patients and clinicians’ best interest, reduction of the operational burden and effective communication. Here, we suggest maintaining effective measures for future trial simplification and to expedite drug development.
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spelling pubmed-72862702020-06-11 Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities Fontana, Elisa Arkenau, Hendrik-Tobias Cancer Treat Rev Article The COVID-19 pandemic affected many activities in the healthcare system including oncology drug development. Clinical trial recruitment was temporary halted in many centres to reduce patients and healthcare workers’ potential exposure to the virus. Conversely, to continue offering treatments for patients already on effective therapies, multiple actions were timely put in place, resulting in simplification of trial-related procedures for patients and clinicians’ best interest, reduction of the operational burden and effective communication. Here, we suggest maintaining effective measures for future trial simplification and to expedite drug development. Elsevier Ltd. 2020-08 2020-06-10 /pmc/articles/PMC7286270/ /pubmed/32544543 http://dx.doi.org/10.1016/j.ctrv.2020.102047 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Fontana, Elisa
Arkenau, Hendrik-Tobias
Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities
title Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities
title_full Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities
title_fullStr Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities
title_full_unstemmed Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities
title_short Oncology clinical trials during the COVID-19 outbreak: Lessons learnt during the crisis and future opportunities
title_sort oncology clinical trials during the covid-19 outbreak: lessons learnt during the crisis and future opportunities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286270/
https://www.ncbi.nlm.nih.gov/pubmed/32544543
http://dx.doi.org/10.1016/j.ctrv.2020.102047
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