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Sulodexide up-regulates glutathione S-transferase P1 by enhancing Nrf2 expression and translocation in human umbilical vein endothelial cells injured by oxygen glucose deprivation
INTRODUCTION: Sulodexide (SDX) is used for the treatment of many vascular disorders due to its anticoagulant, anti-inflammatory and anti-atherosclerotic properties. However, the detailed molecular mechanism of its endothelioprotective action is still not completely understood. There is increasing ev...
Autores principales: | Gabryel, Bożena, Bontor, Klaudia, Jarząbek, Karolina, Plato, Marta, Pudełko, Anna, Machnik, Grzegorz, Urbanek, Tomasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286338/ https://www.ncbi.nlm.nih.gov/pubmed/32542099 http://dx.doi.org/10.5114/aoms.2019.82818 |
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