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Sulodexide up-regulates glutathione S-transferase P1 by enhancing Nrf2 expression and translocation in human umbilical vein endothelial cells injured by oxygen glucose deprivation

INTRODUCTION: Sulodexide (SDX) is used for the treatment of many vascular disorders due to its anticoagulant, anti-inflammatory and anti-atherosclerotic properties. However, the detailed molecular mechanism of its endothelioprotective action is still not completely understood. There is increasing ev...

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Detalles Bibliográficos
Autores principales: Gabryel, Bożena, Bontor, Klaudia, Jarząbek, Karolina, Plato, Marta, Pudełko, Anna, Machnik, Grzegorz, Urbanek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286338/
https://www.ncbi.nlm.nih.gov/pubmed/32542099
http://dx.doi.org/10.5114/aoms.2019.82818

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