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Reprogramming of Lipid Metabolism as a New Driving Force Behind Tauroursodeoxycholic Acid-Induced Neural Stem Cell Proliferation

Recent evidence suggests that neural stem cell (NSC) fate is highly dependent on mitochondrial bioenergetics. Tauroursodeoxycholic acid (TUDCA), an endogenous neuroprotective bile acid and a metabolic regulator, stimulates NSC proliferation and enhances adult NSC pool in vitro and in vivo. In this s...

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Detalles Bibliográficos
Autores principales:	Fernandes, Marta B., Costa, Márcia, Ribeiro, Maria Filipe, Siquenique, Sónia, Sá Santos, Sónia, Martins, Joana, Coelho, Ana V., Silva, Margarida F. B., Rodrigues, Cecília M. P., Solá, Susana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286385/ https://www.ncbi.nlm.nih.gov/pubmed/32582686 http://dx.doi.org/10.3389/fcell.2020.00335

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