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Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals
There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286418/ https://www.ncbi.nlm.nih.gov/pubmed/32524515 http://dx.doi.org/10.1007/s15010-020-01461-0 |
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author | Behrens, Georg M. N. Cossmann, Anne Stankov, Metodi V. Witte, Torsten Ernst, Diana Happle, Christine Jablonka, Alexandra |
author_facet | Behrens, Georg M. N. Cossmann, Anne Stankov, Metodi V. Witte, Torsten Ernst, Diana Happle, Christine Jablonka, Alexandra |
author_sort | Behrens, Georg M. N. |
collection | PubMed |
description | There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5–30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1–2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run. |
format | Online Article Text |
id | pubmed-7286418 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-72864182020-06-11 Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals Behrens, Georg M. N. Cossmann, Anne Stankov, Metodi V. Witte, Torsten Ernst, Diana Happle, Christine Jablonka, Alexandra Infection Brief Report There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5–30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1–2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run. Springer Berlin Heidelberg 2020-06-10 2020 /pmc/articles/PMC7286418/ /pubmed/32524515 http://dx.doi.org/10.1007/s15010-020-01461-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Brief Report Behrens, Georg M. N. Cossmann, Anne Stankov, Metodi V. Witte, Torsten Ernst, Diana Happle, Christine Jablonka, Alexandra Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals |
title | Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals |
title_full | Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals |
title_fullStr | Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals |
title_full_unstemmed | Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals |
title_short | Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals |
title_sort | perceived versus proven sars-cov-2-specific immune responses in health-care professionals |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286418/ https://www.ncbi.nlm.nih.gov/pubmed/32524515 http://dx.doi.org/10.1007/s15010-020-01461-0 |
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