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Metformin revert insulin‐induced oxaliplatin resistance by activating mitochondrial apoptosis pathway in human colon cancer HCT116 cells

BACKGROUND: Several studies have suggested that drug resistance in colon cancer patients with diabetes may be associated with long‐term insulin administration, which in turn decreases the survival rate. Metformin is a commonly used drug to treat diabetes but has been recently demonstrated to have a...

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Detalles Bibliográficos
Autores principales:	Liu, Chao, Liu, Qianqian, Yan, Aiwen, Chang, Hui, Ding, Yuyin, Tao, Junye, Qiao, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286444/ https://www.ncbi.nlm.nih.gov/pubmed/32248666 http://dx.doi.org/10.1002/cam4.3029

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