Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes

The Hippo signalling pathway and its central effector YAP regulate proliferation of cardiomyocytes and growth of the heart. Using genetic models in mice we show that the increased proliferation of embryonal and postnatal cardiomyocytes due to loss of the Hippo-signaling component SAV1 depends on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gründl, Marco, Walz, Susanne, Hauf, Laura, Schwab, Melissa, Werner, Kerstin Marcela, Spahr, Susanne, Schulte, Clemens, Maric, Hans Michael, Ade, Carsten P., Gaubatz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286521/
https://www.ncbi.nlm.nih.gov/pubmed/32469866
http://dx.doi.org/10.1371/journal.pgen.1008818

Ejemplares similares

Ejemplares similares