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Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In times of the Coronavirus disease 2019 (COVID-19) pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurolog...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286830/ https://www.ncbi.nlm.nih.gov/pubmed/32535547 http://dx.doi.org/10.1016/j.ebiom.2020.102822 |
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author | Pawlitzki, Marc Zettl, Uwe K. Ruck, Tobias Rolfes, Leoni Hartung, Hans-Peter Meuth, Sven G. |
author_facet | Pawlitzki, Marc Zettl, Uwe K. Ruck, Tobias Rolfes, Leoni Hartung, Hans-Peter Meuth, Sven G. |
author_sort | Pawlitzki, Marc |
collection | PubMed |
description | Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In times of the Coronavirus disease 2019 (COVID-19) pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurological patients. Uncertainty exists especially because different national medical associations publish different recommendations on the extent to which immunotherapies must be continued, monitored, or possibly switched during the current pandemic. Based on the most recently available data both about the novel coronavirus and the approved immunotherapies for neurological diseases, we provide an updated overview that includes current treatment strategies and the associated COVID-19 risk, but also the potential of immunotherapies to treat COVID-19. |
format | Online Article Text |
id | pubmed-7286830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72868302020-06-11 Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 Pawlitzki, Marc Zettl, Uwe K. Ruck, Tobias Rolfes, Leoni Hartung, Hans-Peter Meuth, Sven G. EBioMedicine Review Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In times of the Coronavirus disease 2019 (COVID-19) pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurological patients. Uncertainty exists especially because different national medical associations publish different recommendations on the extent to which immunotherapies must be continued, monitored, or possibly switched during the current pandemic. Based on the most recently available data both about the novel coronavirus and the approved immunotherapies for neurological diseases, we provide an updated overview that includes current treatment strategies and the associated COVID-19 risk, but also the potential of immunotherapies to treat COVID-19. Elsevier 2020-06-11 /pmc/articles/PMC7286830/ /pubmed/32535547 http://dx.doi.org/10.1016/j.ebiom.2020.102822 Text en © 2020 Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Pawlitzki, Marc Zettl, Uwe K. Ruck, Tobias Rolfes, Leoni Hartung, Hans-Peter Meuth, Sven G. Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 |
title | Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 |
title_full | Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 |
title_fullStr | Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 |
title_full_unstemmed | Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 |
title_short | Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 |
title_sort | merits and culprits of immunotherapies for neurological diseases in times of covid-19 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286830/ https://www.ncbi.nlm.nih.gov/pubmed/32535547 http://dx.doi.org/10.1016/j.ebiom.2020.102822 |
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