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Merits and culprits of immunotherapies for neurological diseases in times of COVID-19

Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In times of the Coronavirus disease 2019 (COVID-19) pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurolog...

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Detalles Bibliográficos
Autores principales: Pawlitzki, Marc, Zettl, Uwe K., Ruck, Tobias, Rolfes, Leoni, Hartung, Hans-Peter, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286830/
https://www.ncbi.nlm.nih.gov/pubmed/32535547
http://dx.doi.org/10.1016/j.ebiom.2020.102822
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author Pawlitzki, Marc
Zettl, Uwe K.
Ruck, Tobias
Rolfes, Leoni
Hartung, Hans-Peter
Meuth, Sven G.
author_facet Pawlitzki, Marc
Zettl, Uwe K.
Ruck, Tobias
Rolfes, Leoni
Hartung, Hans-Peter
Meuth, Sven G.
author_sort Pawlitzki, Marc
collection PubMed
description Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In times of the Coronavirus disease 2019 (COVID-19) pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurological patients. Uncertainty exists especially because different national medical associations publish different recommendations on the extent to which immunotherapies must be continued, monitored, or possibly switched during the current pandemic. Based on the most recently available data both about the novel coronavirus and the approved immunotherapies for neurological diseases, we provide an updated overview that includes current treatment strategies and the associated COVID-19 risk, but also the potential of immunotherapies to treat COVID-19.
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spelling pubmed-72868302020-06-11 Merits and culprits of immunotherapies for neurological diseases in times of COVID-19 Pawlitzki, Marc Zettl, Uwe K. Ruck, Tobias Rolfes, Leoni Hartung, Hans-Peter Meuth, Sven G. EBioMedicine Review Immunosuppression and immunomodulation are valuable therapeutic approaches for managing neuroimmunological diseases. In times of the Coronavirus disease 2019 (COVID-19) pandemic, clinicians must deal with the question of whether immunotherapy should currently be initiated or discontinued in neurological patients. Uncertainty exists especially because different national medical associations publish different recommendations on the extent to which immunotherapies must be continued, monitored, or possibly switched during the current pandemic. Based on the most recently available data both about the novel coronavirus and the approved immunotherapies for neurological diseases, we provide an updated overview that includes current treatment strategies and the associated COVID-19 risk, but also the potential of immunotherapies to treat COVID-19. Elsevier 2020-06-11 /pmc/articles/PMC7286830/ /pubmed/32535547 http://dx.doi.org/10.1016/j.ebiom.2020.102822 Text en © 2020 Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Pawlitzki, Marc
Zettl, Uwe K.
Ruck, Tobias
Rolfes, Leoni
Hartung, Hans-Peter
Meuth, Sven G.
Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
title Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
title_full Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
title_fullStr Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
title_full_unstemmed Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
title_short Merits and culprits of immunotherapies for neurological diseases in times of COVID-19
title_sort merits and culprits of immunotherapies for neurological diseases in times of covid-19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286830/
https://www.ncbi.nlm.nih.gov/pubmed/32535547
http://dx.doi.org/10.1016/j.ebiom.2020.102822
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