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Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections

Recent studies of the neurobiology of the dorsal frontal cortex (FC) of the ferret have illuminated its key role in the attention network, top-down cognitive control of sensory processing, and goal directed behavior. To elucidate the neuroanatomical regions of the dorsal FC, and delineate the bounda...

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Autores principales: Radtke-Schuller, Susanne, Town, Stephen M., Yin, Pingbo, Elgueda, Diego, Schuller, Gerd, Bizley, Jennifer K., Shamma, Shihab A., Fritz, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286872/
https://www.ncbi.nlm.nih.gov/pubmed/32458050
http://dx.doi.org/10.1007/s00429-020-02086-7
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author Radtke-Schuller, Susanne
Town, Stephen M.
Yin, Pingbo
Elgueda, Diego
Schuller, Gerd
Bizley, Jennifer K.
Shamma, Shihab A.
Fritz, Jonathan B.
author_facet Radtke-Schuller, Susanne
Town, Stephen M.
Yin, Pingbo
Elgueda, Diego
Schuller, Gerd
Bizley, Jennifer K.
Shamma, Shihab A.
Fritz, Jonathan B.
author_sort Radtke-Schuller, Susanne
collection PubMed
description Recent studies of the neurobiology of the dorsal frontal cortex (FC) of the ferret have illuminated its key role in the attention network, top-down cognitive control of sensory processing, and goal directed behavior. To elucidate the neuroanatomical regions of the dorsal FC, and delineate the boundary between premotor cortex (PMC) and dorsal prefrontal cortex (dPFC), we placed retrograde tracers in adult ferret dorsal FC anterior to primary motor cortex and analyzed thalamo-cortical connectivity. Cyto- and myeloarchitectural differences across dorsal FC and the distinctive projection patterns from thalamic nuclei, especially from the subnuclei of the medial dorsal (MD) nucleus and the ventral thalamic nuclear group, make it possible to clearly differentiate three separate dorsal FC fields anterior to primary motor cortex: polar dPFC (dPFCpol), dPFC, and PMC. Based on the thalamic connectivity, there is a striking similarity of the ferret’s dorsal FC fields with other species. This possible homology opens up new questions for future comparative neuroanatomical and functional studies.
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spelling pubmed-72868722020-06-15 Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections Radtke-Schuller, Susanne Town, Stephen M. Yin, Pingbo Elgueda, Diego Schuller, Gerd Bizley, Jennifer K. Shamma, Shihab A. Fritz, Jonathan B. Brain Struct Funct Original Article Recent studies of the neurobiology of the dorsal frontal cortex (FC) of the ferret have illuminated its key role in the attention network, top-down cognitive control of sensory processing, and goal directed behavior. To elucidate the neuroanatomical regions of the dorsal FC, and delineate the boundary between premotor cortex (PMC) and dorsal prefrontal cortex (dPFC), we placed retrograde tracers in adult ferret dorsal FC anterior to primary motor cortex and analyzed thalamo-cortical connectivity. Cyto- and myeloarchitectural differences across dorsal FC and the distinctive projection patterns from thalamic nuclei, especially from the subnuclei of the medial dorsal (MD) nucleus and the ventral thalamic nuclear group, make it possible to clearly differentiate three separate dorsal FC fields anterior to primary motor cortex: polar dPFC (dPFCpol), dPFC, and PMC. Based on the thalamic connectivity, there is a striking similarity of the ferret’s dorsal FC fields with other species. This possible homology opens up new questions for future comparative neuroanatomical and functional studies. Springer Berlin Heidelberg 2020-05-26 2020 /pmc/articles/PMC7286872/ /pubmed/32458050 http://dx.doi.org/10.1007/s00429-020-02086-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Article
Radtke-Schuller, Susanne
Town, Stephen M.
Yin, Pingbo
Elgueda, Diego
Schuller, Gerd
Bizley, Jennifer K.
Shamma, Shihab A.
Fritz, Jonathan B.
Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
title Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
title_full Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
title_fullStr Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
title_full_unstemmed Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
title_short Dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
title_sort dorsal prefrontal and premotor cortex of the ferret as defined by distinctive patterns of thalamo-cortical projections
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286872/
https://www.ncbi.nlm.nih.gov/pubmed/32458050
http://dx.doi.org/10.1007/s00429-020-02086-7
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