Cargando…

Urothelial-to-Neural Plasticity Drives Progression to Small Cell Bladder Cancer

We report a comprehensive molecular analysis of 34 cases of small cell carcinoma (SCC) and 84 cases of conventional urothelial carcinoma (UC), with The Cancer Genome Atlas cohort of 408 conventional UC bladder cancers used as the reference. SCCs showed mutational landscapes characterized by nearly u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Guoliang, Bondaruk, Jolanta, Cogdell, David, Wang, Ziqiao, Lee, Sangkyou, Lee, June Goo, Zhang, Shizhen, Choi, Woonyoung, Wang, Yan, Liang, Yu, Wang, Gang, Wang, Ying, Yao, Hui, Dadhania, Vipulkumar, Gao, Jianjun, Logothetis, Christopher, Siefker-Radtke, Arlene, Kamat, Ashish, Dinney, Colin, Theodorescu, Dan, Kimmel, Marek, Wei, Peng, Guo, Charles C., Weinstein, John N., McConkey, David J., Czerniak, Bogdan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286965/ https://www.ncbi.nlm.nih.gov/pubmed/32521509 http://dx.doi.org/10.1016/j.isci.2020.101201

Ejemplares similares

Assessment of Luminal and Basal Phenotypes in Bladder Cancer
por: Guo, Charles C., et al.
Publicado: (2020)

Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use
por: Dadhania, Vipulkumar, et al.
Publicado: (2016)

Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer
por: Ochoa, Andrea E., et al.
Publicado: (2016)

The origin of bladder cancer from mucosal field effects
por: Bondaruk, Jolanta, et al.
Publicado: (2022)

The origin of bladder cancer from mucosal field effects
por: Bondaruk, Jolanta, et al.
Publicado: (2022)

Inhibition of Inducible Heat Shock Protein-70 (Hsp72) Enhances Bortezomib-Induced Cell Death in Human Bladder Cancer Cells
por: Qi, Wei, et al.
Publicado: (2013)

In-Frame cDNA Library Combined with Protein Complementation Assay Identifies ARL11-Binding Partners
por: Lee, Sangkyou, et al.
Publicado: (2012)

p63 Expression Defines a Lethal Subset of Muscle-Invasive Bladder Cancers
por: Choi, Woonyoung, et al.
Publicado: (2012)

Intrinsic subtypes and bladder cancer metastasis
por: McConkey, David J., et al.
Publicado: (2016)

Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior
por: Mobley, Aaron, et al.
Publicado: (2017)

Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting
por: Cheng, Tiewei, et al.
Publicado: (2013)

Erdafitinib for locally advanced or metastatic urothelial carcinoma
por: Siefker-Radtke, Arlene O, et al.
Publicado: (2022)

Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis
por: Roth, Beat, et al.
Publicado: (2016)

Comparison between whole mount tissue preparations and virtual tissue microarray samples for measuring Ki-67 and apoptosis indices in human bladder cancer: A cross-sectional study
por: Oshiro, Hisashi, et al.
Publicado: (2016)

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation
por: Plote, Devin, et al.
Publicado: (2019)

Autophagy is required for crizotinib-induced apoptosis in MET-amplified gastric cancer cells
por: Schroeder, Rebecca D., et al.
Publicado: (2017)

Update on bladder cancer molecular subtypes
por: Fong, Megan Hoi Yan, et al.
Publicado: (2020)

Multimodal kidney‐preserving approach in localised and locally advanced high‐risk upper tract urothelial carcinoma
por: Alhalabi, Omar, et al.
Publicado: (2021)

Detection of Bladder Cancer Using Proteomic Profiling of Urine Sediments
por: Majewski, Tadeusz, et al.
Publicado: (2012)

Frequent truncating mutations of STAG2 in bladder cancer
por: Solomon, David A., et al.
Publicado: (2013)

ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma
por: Kim, Michael P., et al.
Publicado: (2011)

A Phase II, single-arm study of nivolumab in patients with metastatic or unresectable urothelial cancer who have progressed following treatment with a platinum agent
por: Sharma, Padmanee, et al.
Publicado: (2015)

A Brief Measure of Parental Wellbeing for Use in Evaluations of Family-Centred Interventions for Children with Developmental Disabilities
por: McConkey, Roy
Publicado: (2020)

Responding to Autism in Low and Middle Income Countries (Lmic): What to Do and What Not to Do
por: McConkey, Roy
Publicado: (2022)

Administración financiera por objetivos
por: McConkey, Dale D.
Publicado: (1982)

12 guiding premises of pediatric cochlear implant habilitation
por: McConkey Robbins, Amy
Publicado: (2018)

THE RELATION OF VITAMIN C DEFICIENCY TO INTESTINAL TUBERCULOSIS IN THE GUINEA PIG
por: McConkey, Mack, et al.
Publicado: (1933)

Topics in chemical physics
por: Prock, Alfred, et al.
Publicado: (1962)

Insiders’ Insight: Discrimination against Indigenous Peoples through the Eyes of Health Care Professionals
por: Wylie, Lloy, et al.
Publicado: (2018)

Neurophysiological Changes Induced by Chronic Toxoplasma gondii Infection
por: Tedford, Ellen, et al.
Publicado: (2017)

Editorial: Recent Advances in Diagnosis and Management of Urothelial Carcinoma
por: Ku, Ja Hyeon, et al.
Publicado: (2021)

Outcomes of Patients with Advanced Urothelial Carcinoma after Anti–programmed Death-(ligand) 1 Therapy by Fibroblast Growth Factor Receptor Gene Alteration Status: An Observational Study
por: Rezazadeh Kalebasty, Arash, et al.
Publicado: (2022)

Fluid intake, genetic variants of UDP-glucuronosyltransferases, and bladder cancer risk
por: Wang, J, et al.
Publicado: (2013)

A modelling approach to evaluate the long-term effect of soil texture on spring wheat productivity under a rain-fed condition
por: He, Yong, et al.
Publicado: (2014)

Increasing incidence of adenocarcinoma of the gastric cardia and adjacent sites.
por: Powell, J., et al.
Publicado: (1990)

Parents of children with autism spectrum disorder and children with intellectual disabilities and their stress and general health
por: Samadi, Sayyed Ali, et al.
Publicado: (2009)

Autism in Developing Countries: Lessons from Iran
por: Samadi, Sayyed Ali, et al.
Publicado: (2011)

An audit of knowledge, attitude and sexual practise of HIV positive patients in Beaumont Hospital.
por: McMahon, David, et al.
Publicado: (2015)

Perspectives on Inclusive Education of Preschool Children with Autism Spectrum Disorders and Other Developmental Disabilities in Iran
por: Samadi, Sayyed Ali, et al.
Publicado: (2018)

Letter to the Editor: Bacillus Calmette-Guerin (BCG) Treatment Failures with Non-Muscle Invasive Bladder Cancer: A Data-Driven Definition for BCG Unresponsive Disease
por: Li, Roger, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mtf0k62t9gcc4kobb4pq2cpalr