FoxM1-dependent and fatty acid oxidation-mediated ROS modulation is a cell-intrinsic drug resistance mechanism in cancer stem-like cells

Increased oxidative phosphorylation (OXPHOS) and reactive oxygen species (ROS) levels are inherently linked. ROS are essential signaling molecules, with detrimental effects when produced in excess during chemotherapy, leading to cell death. Cancer stem-like cells (CSCs) are a subpopulation of tumor...

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Detalles Bibliográficos
Autores principales: Choi, Hae-Ji, Jhe, Yoo-Lim, Kim, Jungmin, Lim, Ju Yeon, Lee, Jae Eun, Shin, Min-Kyue, Cheong, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286985/
https://www.ncbi.nlm.nih.gov/pubmed/32521504
http://dx.doi.org/10.1016/j.redox.2020.101589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286985/
https://www.ncbi.nlm.nih.gov/pubmed/32521504
http://dx.doi.org/10.1016/j.redox.2020.101589

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