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One cysteine is enough: A monothiol Grx can functionally replace all cytosolic Trx and dithiol Grx
Glutaredoxins are small proteins of the thioredoxin superfamily that are present throughout life. Most glutaredoxins fall into two major subfamilies. Class I glutaredoxins are glutathione-dependent thiol-disulfide oxidoreductases whilst class II glutaredoxins coordinate Fe–S clusters. Class I glutar...
Autores principales: | Zimmermann, Jannik, Oestreicher, Julian, Hess, Steffen, Herrmann, Johannes M., Deponte, Marcel, Morgan, Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286987/ https://www.ncbi.nlm.nih.gov/pubmed/32521506 http://dx.doi.org/10.1016/j.redox.2020.101598 |
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