A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites

Stress response pathways are critical for cellular homeostasis, promoting survival through adaptive changes in gene expression and metabolism. They play key roles in numerous diseases and are implicated in cancer progression and chemoresistance. However, the underlying mechanisms are only poorly und...

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Detalles Bibliográficos
Autores principales: Reich, Stefan, Nguyen, Chi D. L., Has, Canan, Steltgens, Sascha, Soni, Himanshu, Coman, Cristina, Freyberg, Moritz, Bichler, Anna, Seifert, Nicole, Conrad, Dominik, Knobbe-Thomsen, Christiane B., Tews, Björn, Toedt, Grischa, Ahrends, Robert, Medenbach, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287054/
https://www.ncbi.nlm.nih.gov/pubmed/32522993
http://dx.doi.org/10.1038/s41467-020-16747-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287054/
https://www.ncbi.nlm.nih.gov/pubmed/32522993
http://dx.doi.org/10.1038/s41467-020-16747-y

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